Computer simulation studies of biological membranes: progress, promise and pitfalls

被引：57

作者：

Jakobsson, E

机构：

[1] Department of Molecular and Integrative Physiology, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 09期

基金：

美国国家卫生研究院;

关键词：

MOLECULAR-DYNAMICS SIMULATIONS; LIPID BILAYER-MEMBRANE; SURFACE-TENSION; PHOSPHOLIPID-BILAYERS; BOUNDARY-CONDITIONS; GRAMICIDIN-A; X-RAY; WATER; TRANSPORT; CHANNEL;

D O I：

10.1016/S0968-0004(97)01096-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Because of the complexity of biological membranes, computer simulations are useful adjuncts to experimental work in their study. Simulations of model membranes have provided new insights, Progress in simulating more biologically realistic membranes will require further development of statistical mechanical theory applied specifically to these systems, in conjunction with the use of powerful computers.

引用

页码：339 / 344

页数：6

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