1α,25-dihydroxyvitamin D3 -: Not just a calciotropic hormone

被引：9

作者：

Kumar, R

机构：

[1] Mayo Clin & Mayo Fdn, Dept Med, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Dept Biochem, Rochester, MN 55905 USA

[3] Mayo Clin & Mayo Fdn, Dept Mol Biol, Rochester, MN 55905 USA

来源：

NEPHRON | 2002年 / 91卷 / 04期

关键词：

vitamin D; 1; alpha; 25(OH)(2)D-3; growth factors; immune function;

D O I：

10.1159/000065015

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

1alpha,25-Dihydroxyvitamin D-3, the hormonal form of vitamin D-3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1alpha,25-dihydroxyvitamin D-3 regulates cellular growth, alters central nervous system function, and immune function. Copyright (C) 2002 S. Karger AG, Basel.

引用

收藏

页码：576 / 581

页数：6

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