Ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating

被引:297
作者
Leadbeater, NE [1 ]
Marco, M [1 ]
机构
[1] Kings Coll London, Dept Chem, London WC2R 2LS, England
关键词
D O I
10.1021/ol0263907
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report the ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating. Our methodology uses low palladium loadings (0.4 mol %), is fast (5-10 min reaction time), and is useful for couplings involving boronic acids and aryl iodides, bromides, and chlorides.
引用
收藏
页码:2973 / 2976
页数:4
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