3 beta,4 beta-epoxy-5 beta-androstan-17-one

被引：8

作者：

Andrade, LCR ^{[1
]}

Paixao, JA ^{[1
]}

deAlmeida, MJ ^{[1
]}

daSilva, EJT ^{[1
]}

Melo, MLSE ^{[1
]}

Neves, ASC ^{[1
]}

机构：

[1] UNIV COIMBRA,FAC FARM,CTR ESTUD FARMACEUT,QUIM FARMACEUT LAB,P-3000 COIMBRA,PORTUGAL

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1997年 / 53卷

关键词：

D O I：

10.1107/S0108270197002138

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound, C19H28O2, has the configuration of a 5 beta epimer with an epoxy O atom at 3 beta,4 beta. The asymmetric unit contains two molecules with almost identical geometry, Cohesion of the crystal can be attributed to weak intermolecular C-H ... O and van der Waals interactions.

引用

页码：938 / 940

页数：3

共 13 条

[1] CONFORMATION OF NON-AROMATIC RING COMPOUNDS .25. GEOMETRY AND CONFORMATION OF RING D IN SOME STEROIDS FROM X-RAY STRUCTURE DETERMINATIONS [J].

ALTONA, C ;

GEISE, HJ ;

ROMERS, C .

TETRAHEDRON, 1968, 24 (01) :13-&

[2] Novel approach to the synthesis of the aromatase inhibitor 4-hydroxyandrost-4-ene-3,17-dione (4-OHA) [J].

daSilva, EJT ;

Melo, MLSE ;

Neves, ASC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1996, (14) :1649-1650

[3]

Duax W.L., 1975, Atlas of Steroid Structure, V1

[4]

*ENR NON, 1989, CAD 4 SOFTW VERS 5

[5] ON ENANTIOMORPH-POLARITY ESTIMATION [J].

FLACK, HD .

ACTA CRYSTALLOGRAPHICA SECTION A, 1983, 39 (NOV) :876-881

[6]

FRENZ BA, 1985, ENRAF NONIUS SDP PLU

[7]

Johnson C. K., 1976, ORNL5138

[8] MAIN-PART ISOSTRUCTURALISM OF SEVERAL CARDENOLIDES AND BUFADIENOLIDES - STRUCTURES OF 3 CARDENOLIDES - (21S)-METHYLDIGITOXIGENIN, UZARIGENIN AND SARMENTOGENIN METHANOL SOLVATE [J].

KALMAN, A ;

ARGAY, G ;

SCHARFENBERGPFEIFFER, D ;

HOHNE, E ;

RIBAR, B .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS, 1991, 47 :68-77

[9]

MAIN P, 1982, MULTAN SYSTEM COMPUT

[10] 3 alpha,4 alpha-epoxy-5 alpha-androstan-17-one [J].

Paixao, JA ;

Silva, MR ;

deAlmeida, MJ ;

daSilva, EJT ;

Melo, MLSE ;

Neves, ASC .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1997, 53 :347-349

← 1 2 →