Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs

被引:63
作者
Ghannam, Malik [1 ]
Jumah, Fareed [1 ]
Mansour, Shaden [1 ]
Samara, Amjad [1 ]
Alkhdour, Saja [1 ]
Alzuabi, Muayad A. [2 ]
Aker, Loai [1 ]
Adeeb, Nimer [3 ]
Massengale, Justin [3 ]
Oskouian, Rod J. [5 ]
Tubbs, R. Shane [4 ,5 ]
机构
[1] An Najah Natl Univ Hosp, Nablus, Palestine
[2] Ain Shams Univ, Neurosci Inst, Cairo, Egypt
[3] Boston Univ, Boston Med Ctr, Dept Neurosurg, Boston, MA 02215 USA
[4] St Georges Univ, Dept Anat Sci, St Georges, Grenada
[5] Seattle Sci Fdn, Seattle, WA 98122 USA
关键词
anatomy; molecular; biology; embryology; imaging; intervertebral disc; NUCLEUS PULPOSUS CELLS; TISSUE-GROWTH-FACTOR; LOW-BACK-PAIN; GENE-EXPRESSION; EXTRACELLULAR-MATRIX; NOTOCHORDAL CELLS; ANNULUS FIBROSUS; VERTEBRAL COLUMN; END-PLATE; HYDROSTATIC-PRESSURE;
D O I
10.1002/ca.22822
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100123 [人体微生态学]; 100210 [外科学];
摘要
The intervertebral disc (IVD) is a joint unique in structure and functions. Lying between adjacent vertebrae, it provides both the primary support and the elasticity required for the spine to move stably. Various aspects of the IVD have long been studied by researchers seeking a better understanding of its dynamics, aging, and subsequent disorders. In this article, we review the surgical anatomy, imaging modalities, and molecular biology of the lumbar IVD. Clin. Anat. 30:251-266, 2017. (c) 2017 Wiley Periodicals, Inc.
引用
收藏
页码:251 / 266
页数:16
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