Additive effect of beraprost on pulmonary vasodilation by inhaled nitric oxide in children with pulmonary hypertension

被引:24
作者
Ichida, F [1 ]
Uese, K [1 ]
Tsubata, S [1 ]
Hashimoto, I [1 ]
Hamamichi, Y [1 ]
Fukahara, K [1 ]
Murakami, A [1 ]
Miyawaki, T [1 ]
机构
[1] TOYAMA MED & PHARMACEUT UNIV,DEPT SURG 1,TOYAMA 93001,JAPAN
关键词
D O I
10.1016/S0002-9149(97)00447-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Combined administration of inhaled nitric oxide and beraprost sodium resulted in a more intense decrease in pulmonary vascular resistance than nitric oxide given alone (mean -33% vs -45%, p < 0.05), without serious systemic hypotension. Combined therapy with nitric oxide and beraprost sodium is highly desireable in treating primary and secondary pulmonary hypertension in children.
引用
收藏
页码:662 / &
页数:4
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