Antibody-Based Sensors: Principles, Problems and Potential for Detection of Pathogens and Associated Toxins

被引:249
作者
Byrne, Barry [1 ,2 ]
Stack, Edwina [2 ]
Gilmartin, Niamh [2 ,3 ]
O'Kennedy, Richard [1 ,2 ,3 ]
机构
[1] Dublin City Univ, CBAS, Dublin 9, Ireland
[2] Dublin City Univ, NCSR, Dublin 9, Ireland
[3] Dublin City Univ, BDI, Dublin 9, Ireland
来源
SENSORS | 2009年 / 9卷 / 06期
基金
爱尔兰科学基金会;
关键词
pathogen; antibody; biosensor; electrochemical; surface-plasmon resonance; assay development; SURFACE-PLASMON RESONANCE; ESCHERICHIA-COLI O157-H7; REAL-TIME PCR; ADDRESSABLE POTENTIOMETRIC SENSOR; LINKED-IMMUNOSORBENT-ASSAY; BACILLUS-ANTHRACIS SPORES; SELF-ASSEMBLED MONOLAYER; SINGLE-CHAIN ANTIBODIES; LISTERIA-MONOCYTOGENES; RAPID DETECTION;
D O I
10.3390/s90604407
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for 'on-site' analysis. Particular emphasis is placed on the detection of foodborne bacterial pathogens, such as Escherichia coli and Listeria monocytogenes, and additional examples relating to the monitoring of fungal pathogens, viruses, mycotoxins, marine toxins and parasites are also provided.
引用
收藏
页码:4407 / 4445
页数:39
相关论文
共 184 条
[1]   Development of immunosensor based on OWLS technique for determining Aflatoxin B1 and Ochratoxin A [J].
Adanyi, N. ;
Levkovets, I. A. ;
Rodriguez-Gil, S. ;
Ronald, A. ;
Varadi, M. ;
Szendro, I. .
BIOSENSORS & BIOELECTRONICS, 2007, 22 (06) :797-802
[2]   Protocol development using an electronic nose for differentiating E-coli strains [J].
Alocija, EC ;
Ritchie, NL ;
Grooms, DL .
IEEE SENSORS JOURNAL, 2003, 3 (06) :801-805
[3]   Improved fluoroimmunoassays using the dye Alexa Fluor 647 with the RAPTOR, a fiber optic biosensor [J].
Anderson, GP ;
Nerurkar, NL .
JOURNAL OF IMMUNOLOGICAL METHODS, 2002, 271 (1-2) :17-24
[4]  
ANDRISWIDHOPF J, 2001, PHAGE DISPLAY LAB MA
[5]   Use of miniaturized protein arrays for Escherichia coli O serotyping [J].
Anjum, Muna F. ;
Tucker, James D. ;
Sprigings, Katherine A. ;
Woodward, Martin J. ;
Ehricht, Ralf .
CLINICAL AND VACCINE IMMUNOLOGY, 2006, 13 (05) :561-567
[6]  
[Anonymous], 1993, IMMUNOMETHODS
[7]   The impact of glycosylation on the biological function and structure of human immunoglobulins [J].
Arnold, James N. ;
Wormald, Mark R. ;
Sim, Robert B. ;
Rudd, Pauline M. ;
Dwek, Raymond A. .
ANNUAL REVIEW OF IMMUNOLOGY, 2007, 25 :21-50
[8]   Proteomic characterization of enterohernorrhagic Escherichia coli O157:H7 in the oxidation-induced viable but non-culturable state [J].
Asakura, Hiroshi ;
Panutdaporn, Nantika ;
Kawamoto, Keiko ;
Igimi, Shizunobu ;
Yamamoto, Shigeki ;
Makin, Sou-ichi .
MICROBIOLOGY AND IMMUNOLOGY, 2007, 51 (09) :875-881
[9]   Evaluation of antibody immobilization methods for piezoelectric biosensor application [J].
Babacan, S ;
Pivarnik, P ;
Letcher, S ;
Rand, AG .
BIOSENSORS & BIOELECTRONICS, 2000, 15 (11-12) :615-621
[10]   Identification of Salmonella-inoculated beef using a portable electronic nose system [J].
Balasubramanian, S ;
Panigrahi, S ;
Logue, CM ;
Marchello, M ;
Sherwood, JS .
JOURNAL OF RAPID METHODS AND AUTOMATION IN MICROBIOLOGY, 2005, 13 (02) :71-95