Antibody-Based Sensors: Principles, Problems and Potential for Detection of Pathogens and Associated Toxins

被引：249

作者：

Byrne, Barry ^{[1
,2
]}

Stack, Edwina ^{[2
]}

Gilmartin, Niamh ^{[2
,3
]}

O'Kennedy, Richard ^{[1
,2
,3
]}

机构：

[1] Dublin City Univ, CBAS, Dublin 9, Ireland

[2] Dublin City Univ, NCSR, Dublin 9, Ireland

[3] Dublin City Univ, BDI, Dublin 9, Ireland

来源：

SENSORS | 2009年 / 9卷 / 06期

基金：

爱尔兰科学基金会;

关键词：

pathogen; antibody; biosensor; electrochemical; surface-plasmon resonance; assay development; SURFACE-PLASMON RESONANCE; ESCHERICHIA-COLI O157-H7; REAL-TIME PCR; ADDRESSABLE POTENTIOMETRIC SENSOR; LINKED-IMMUNOSORBENT-ASSAY; BACILLUS-ANTHRACIS SPORES; SELF-ASSEMBLED MONOLAYER; SINGLE-CHAIN ANTIBODIES; LISTERIA-MONOCYTOGENES; RAPID DETECTION;

D O I：

10.3390/s90604407

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for 'on-site' analysis. Particular emphasis is placed on the detection of foodborne bacterial pathogens, such as Escherichia coli and Listeria monocytogenes, and additional examples relating to the monitoring of fungal pathogens, viruses, mycotoxins, marine toxins and parasites are also provided.

引用

页码：4407 / 4445

页数：39

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