PDMS-based microfluidic devices for biomedical applications

被引：412

作者：

Fujii, T ^{[1
]}

机构：

[1] Univ Tokyo, Inst Ind Sci, Meguro Ku, Tokyo 1538505, Japan

来源：

MICROELECTRONIC ENGINEERING | 2002年 / 61-2卷

关键词：

microfluidics; micro-TAS; lab-on-a-chip; PDMS;

D O I：

10.1016/S0167-9317(02)00494-X

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Microfluidic devices provide a number of advantageous features for microscale biochemical systems for analysis and/or synthesis. A PDMS (polydimethylsiloxane) microchip, for instance, which has microchannels for electrophoretic separation can be easily fabricated through a molding process. Sealing of those channels does not need any elaborate bonding processes which are usually required for glass chips. We have been working on PDMS-based microfluidic devices for biomedical applications, where microreactors, microchips for capillary gel electrophoresis, and hydrophobic vent valves are successfully fabricated and operated. Fundamentals of PDMS-based microfluidic devices and their functions are described as well as the experimental results. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：907 / 914

页数：8

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