Unveiling ribosomal structures: the final phases

被引:24
作者
van Heel, M [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Biochem, London SW7 2AY, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/S0959-440X(00)00077-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Unprecedented insights into the structure of the ribosome have been gained recently: X-ray crystallographic studies have yielded 5-9 Angstrom resolution structures and cryo-electron microscopy has elucidated the structure of the Escherichia coli ribosome in different functional states. A 7.5 Angstrom cryo-electron microscopy structure of the large subunit indicates that this technique is still in the race to determine the ribosome structure.
引用
收藏
页码:259 / 264
页数:6
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