Solution phase combinatorial synthesis of arylpiperazines

被引:38
作者
Neuville, L [1 ]
Zhu, JP [1 ]
机构
[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE
关键词
D O I
10.1016/S0040-4039(97)00831-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A solution phase combinatorial synthesis of aryl piperazines 1 and 2 is described based on the SNAr reaction and Schotten-Baumann acylation. The use of excess reagent is allowed and pure arylpiperazines 1 and 2 were obtained by simple acid/base washing. (C) 1997 Published by Elsevier Science Ltd.
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页码:4091 / 4094
页数:4
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