Cystic kidney diseases: All roads lead to the cilium

被引：59

作者：

Zhang, QH ^{[1
]}

Taulman, PD ^{[1
]}

Yoder, BK ^{[1
]}

机构：

[1] Univ Alabama Birmingham, Dept Cell Biol, Birmingham, AL 35294 USA

来源：

PHYSIOLOGY | 2004年 / 19卷

关键词：

D O I：

10.1152/physiol.00003.2004

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Cystic kidney disorders are one of the leading causes of end-stage renal disease. Numerous experimental animal models have been used to understand the disease pathogenesis. Recent advancements in this field have provided a surprising finding: that many of the proteins associated with cystic kidney disease localize to a nearly forgotten organelle, the primary cilium.

引用

页码：225 / 230

页数：6

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