A new metal-free access to vitamin K3

被引：27

作者：

Bohle, Anne

Schubert, Anett

Sun, Yu

Thiel, Werner R.

机构：

[1] Tech Univ Kaiserslautern, Fachbereich Chem, D-67663 Kaiserslautern, Germany

[2] Tech Univ Chemnitz, Inst Chem, D-09111 Chemnitz, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2006年 / 348卷 / 09期

关键词：

acid catalysis; hydrogen peroxide; menadione; oxidation; vitamin K3;

D O I：

10.1002/adsc.200505491

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

2-Methylnaphthalene is oxidized in about 80% yield with 7-9/1 regioselectivity to 2-methyl-1,4-naphthoquinone by hydrogen peroxide with a strong mineral acid as the catalyst. No (transition) metal catalyst is required for this transformation.

引用

页码：1011 / 1015

页数：5

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