BACTERIAL FATTY ACID SYNTHESIS AND ITS RELATIONSHIPS WITH POLYKETIDE SYNTHETIC PATHWAYS

被引：222

作者：

Cronan, John E. ^{[1
,2
]}

Thomas, Jacob ^{[1
]}

机构：

[1] Univ Illinois, Dept Microbiol, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA

来源：

COMPLEX ENZYMES IN MICROBIAL NATURAL PRODUCT BIOSYNTHESIS, PART B: POLYKETIDES, AMINOCOUMARINS AND CARBOHYDRATES | 2009年 / 459卷

关键词：

ACYL CARRIER PROTEIN; STREPTOMYCES-COELICOLOR A3(2); ESCHERICHIA-COLI; SYNTHASE-III; PHOSPHOPANTETHEINYL TRANSFERASE; NUCLEOTIDE-SEQUENCE; REDUCTASE FABI; ACTIVE-SITE; THIOLACTOMYCIN RESISTANCE; STREPTOCOCCUS-PNEUMONIAE;

D O I：

10.1016/S0076-6879(09)04617-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.

引用

页码：395 / 433

页数：39

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