BACTERIAL FATTY ACID SYNTHESIS AND ITS RELATIONSHIPS WITH POLYKETIDE SYNTHETIC PATHWAYS

被引：222

作者：

Cronan, John E. ^{[1
,2
]}

Thomas, Jacob ^{[1
]}

机构：

[1] Univ Illinois, Dept Microbiol, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA

来源：

COMPLEX ENZYMES IN MICROBIAL NATURAL PRODUCT BIOSYNTHESIS, PART B: POLYKETIDES, AMINOCOUMARINS AND CARBOHYDRATES | 2009年 / 459卷

关键词：

ACYL CARRIER PROTEIN; STREPTOMYCES-COELICOLOR A3(2); ESCHERICHIA-COLI; SYNTHASE-III; PHOSPHOPANTETHEINYL TRANSFERASE; NUCLEOTIDE-SEQUENCE; REDUCTASE FABI; ACTIVE-SITE; THIOLACTOMYCIN RESISTANCE; STREPTOCOCCUS-PNEUMONIAE;

D O I：

10.1016/S0076-6879(09)04617-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.

引用

页码：395 / 433

页数：39

共 146 条

[91] Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography [J].

Oefner, Christian ;

Schulz, Henk ;

D'Arcy, Allan ;

Dale, Glenn E. .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2006, 62 :613-618

[92] High copy number plasmids compatible with commonly used cloning vectors [J].

Phillips, GJ ;

Park, SK ;

Huber, D .

BIOTECHNIQUES, 2000, 28 (03) :400-+

[93]

POSTBEITTENMILLER D, 1991, J BIOL CHEM, V266, P1858

[94]

PRESCOTT DJ, 1972, ADV ENZYMOL RAMB, V36, P269

[95] Lipopolysaccharide endotoxins [J].

Raetz, CRH ;

Whitfield, C .

ANNUAL REVIEW OF BIOCHEMISTRY, 2002, 71 :635-700

[96]

RAWLINGS M, 1992, J BIOL CHEM, V267, P5751

[97]

RAWLINGS M, 1993, ISOLATION CHARACTERI

[98] ACTIVATION OF LONG-CHAIN FATTY-ACIDS WITH ACYL CARRIER PROTEIN - DEMONSTRATION OF A NEW ENZYME, ACYL-ACYL CARRIER PROTEIN [J].

RAY, TK ;

CRONAN, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (12) :4374-4378

[99] Relationships between fatty acid and polyketide synthases from Streptomyces coelicolor A3(2): Characterization of the fatty acid synthase acyl carrier protein [J].

Revill, WP ;

Bibb, MJ ;

Hopwood, DA .

JOURNAL OF BACTERIOLOGY, 1996, 178 (19) :5660-5667

[100] PURIFICATION OF A MALONYLTRANSFERASE FROM STREPTOMYCES-COELICOLOR A3(2) AND ANALYSIS OF ITS GENETIC DETERMINANT [J].

REVILL, WP ;

BIBB, MJ ;

HOPWOOD, DA .

JOURNAL OF BACTERIOLOGY, 1995, 177 (14) :3946-3952

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