Wavelength ratiometric fluorescent probes for glucose

被引：1

作者：

DiCesare, N ^{[1
]}

Lakowicz, JR ^{[1
]}

机构：

[1] Univ Maryland, Dept Biochem & Mol Biol, Ctr Fluorescence Spect, Baltimore, MD 21201 USA

来源：

CLINICAL DIAGNOSTIC SYSTEMS: TECHNOLOGIES AND INSTRUMENTATION | 2002年 / 4625卷

关键词：

boronic acid; fluorescent probe; fluorescence sensing; glucose; charge-transfer in the excited state;

D O I：

10.1117/12.469790

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have developed a new series of glucose sensitive fluorophores that display shifts in emission wavelengths upon the binding of glucose. Complexation of glucose with the boronic acid moiety changes both its orbital hybridization and its ability to accept and donate electrons. This change results in distinct emission spectra for the fluorophores when free in solution or complexed with glucose.

引用

页码：152 / 159

页数：8

共 37 条

[1] Hypoglycemia in the diabetes control and complications trial [J].

不详 .

DIABETES, 1997, 46 (02) :271-286

[2]

[Anonymous], TOPICS FLUORESCENCE

[3]

Burmeister JJ, 1998, PHOTOCHEM PHOTOBIOL, V67, P50, DOI 10.1562/0031-8655(1998)067<0050:PFNBGS>2.3.CO

[4]

[5] SUBCUTANEOUS IMPLANTATION OF A FERROCENE-MEDIATED GLUCOSE SENSOR IN PIGS [J].

CLAREMONT, DJ ;

SAMBROOK, IE ;

PENTON, C ;

PICKUP, JC .

DIABETOLOGIA, 1986, 29 (11) :817-821

[6] EVALUATION OF A NEW SYSTEM FOR SELF BLOOD-GLUCOSE MONITORING [J].

CLARKE, WL ;

BECKER, DJ ;

COX, D ;

SANTIAGO, JV ;

WHITE, NH ;

BETSCHART, J ;

ECKENRODE, K ;

LEVANDOSKI, LA ;

PRUSINSKI, EA ;

SIMINEIRO, LM ;

SNYDER, AL ;

TIDEMAN, AM ;

YAEGER, T .

DIABETES RESEARCH AND CLINICAL PRACTICE, 1988, 4 (03) :209-214

[7] A thermophilic apoglucose dehydrogenase as nonconsuming glucose sensor [J].

D'Auria, S ;

Di Cesare, N ;

Gryczynski, Z ;

Gryczynski, I ;

Rossi, M ;

Lakowicz, JR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 274 (03) :727-731

[8] ALLOSTERIC INTERACTION OF METAL-IONS WITH SACCHARIDES IN A CROWNED DIBORONIC ACID [J].

DENG, G ;

JAMES, TD ;

SHINKAI, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (11) :4567-4572

[9] Wavelength-ratiometric probes for saccharides based on donor-acceptor diphenylpolyenes [J].

Di Cesare, N ;

Lakowicz, JR .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2001, 143 (01) :39-47

[10] Spectral properties of fluorophores combining the boronic acid group with electron donor or withdrawing groups. Implication in the development of fluorescence probes for saccharides [J].

DiCesare, N ;

Lakowicz, JR .

JOURNAL OF PHYSICAL CHEMISTRY A, 2001, 105 (28) :6834-6840

← 1 2 3 4 →