Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis

被引:357
作者
Hull, AK [1 ]
Vij, R [1 ]
Celenza, JL [1 ]
机构
[1] Boston Univ, Dept Biol, Boston, MA 02215 USA
关键词
auxin; metabolism; glucosinolates;
D O I
10.1073/pnas.040569997
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Plants synthesize numerous secondary metabolites that are used as developmental signals or as defense against pathogens, Tryptophan (Trp)-derived secondary metabolites include camalexin, indole glucosinolates, and indole-3-acetic acid (IAA); however, the steps in their synthesis from Trp or its precursors remain unclear. We have identified two Arabidopsis cytochrome P450s (CYP79B2 and CYP79B3) that can convert Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.
引用
收藏
页码:2379 / 2384
页数:6
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