Personalised dosing: Printing a dose of one's own medicine

被引：191

作者：

Alomari, Mustafa ^{[1
]}

Mohamed, Fatima H. ^{[1
]}

Basit, Abdul W. ^{[1
]}

Gaisford, Simon ^{[1
]}

机构：

[1] UCL, UCL Sch Pharm, London WC1N 1AX, England

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2015年 / 494卷 / 02期

关键词：

Ink-jet printing; Pharmaceutical; Narrow therapeutic index; Personalised medicine; Piezoelectric printer; ORAL DOSAGE FORMS; DRUG-DELIVERY; SALBUTAMOL SULFATE; INKJET; FABRICATION; ACCURACY; DEVICES; FORMULATIONS; TECHNOLOGIES; UNIFORMITY;

D O I：

10.1016/j.ijpharm.2014.12.006

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Ink-jet printing is a versatile, precise and relatively inexpensive method of depositing small volumes of solutions with remarkable accuracy and repeatability. Although developed primarily as a technology for image reproduction, its areas of application have expanded significantly in recent years. It is particularly suited to the manufacture of low dose medicines or to short production runs and so offers a potential manufacturing solution for the paradigm of personalised medicines. This review discusses the technical and clinical aspects of ink-jet printing that must be considered in order for the technology to become widely adopted in the pharmaceutical arena and considers applications in the literature. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：568 / 577

页数：10

共 94 条

[1]

Inkjet Printing of Layer-by-Layer Assembled Poly(lactide) Stereocomplex with Encapsulated Proteins [J].