Pyrrolidinones from the Ascomycete Fungus Albonectria rigidiuscula

被引：49

作者：

Li, Jian ^{[1
,2
]}

Liu, Shuchun ^{[1
]}

Niu, Shubin ^{[1
]}

Zhuang, Wenying ^{[1
]}

Che, Yongsheng ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Microbiol, Key Lab Systemat Mycol & Lichenol, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 12期

基金：

中国国家自然科学基金;

关键词：

TETRAMIC ACIDS; DERIVATIVES;

D O I：

10.1021/np900619z

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The new pyrrolidinones, rigidiusculamides A-D (1-4), have been isolated from the crude extract of the ascomycete fungus Albonectria rigidiuscula. The structures of these compounds were elucidated primarily by NMR experiments. The absolute configuration of the 3,4-diol moieties in 1 and 4 was assigned using Snatzke's method. Compounds 1 and 2 showed modest cytotoxicity against the human tumor cell lines HeLa and MCF-7.

引用

收藏

页码：2184 / 2187

页数：4

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