A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

被引:118
作者
Lundwall, Å [1 ]
Band, V
Blaber, M
Clements, JA
Courty, Y
Diamandis, EP
Fritz, H
Liija, H
Malm, J
Maltais, LJ
Olsson, AY
Petraki, C
Scorilas, A
Sotiropoulou, G
Stenman, UH
Stephan, C
Talieri, M
Yousef, GM
机构
[1] Lund Univ, Univ Hosp MAS, Dept Lab Med, S-20502 Malmo, Sweden
[2] Evanston Northwestern Healthcare Res Inst, Dept Med, Evanston, IL 60201 USA
[3] Florida State Univ, Coll Med, Dept Biomed Sci, Tallahassee, FL 32306 USA
[4] Queensland Univ Technol, Sch Life Sci, Brisbane, Qld 4001, Australia
[5] Queensland Univ Technol, Ctr Sci Res, Brisbane, Qld 4001, Australia
[6] Univ Tours, INSERM, U618, F-37000 Tours, France
[7] Mt Sinai Hosp, Dept Pathol & Lab Med, Toronto, ON M5G 1X5, Canada
[8] Univ Munich, Surg Dept City, Div Clin Biochem, D-80336 Munich, Germany
[9] Mem Sloan Kettering Canc Ctr, Dept Clin Labs, New York, NY 10021 USA
[10] Mem Sloan Kettering Canc Ctr, Dept Urol, New York, NY 10021 USA
[11] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA
[12] Jackson Lab, MGNC, Bar Harbor, ME 04609 USA
[13] Evangelismos Med Ctr, Dept Pathol, GR-11364 Athens, Greece
[14] Inst Canc Res, Sutton SM2 5NG, Surrey, England
[15] Univ Athens, Dept Biochem & Mol Biol, GR-15701 Athens, Greece
[16] Univ Patras, Sch Hlth Sci, Dept Pharm, GR-26500 Patras, Greece
[17] Univ Helsinki, Cent Hosp, Dept Clin Chem, FIN-00029 Helsinki, Finland
[18] Univ Med Charite, Dept Urol, D-10098 Berlin, Germany
[19] Saint Savas Hosp, G Papanicolaou Res Ctr Oncol, GR-11522 Athens, Greece
[20] Hlth Sci Corp St Johns, Discipline Pathol, St John, NF A1B 3V6, Canada
[21] Umea Univ, Dept Publ Hlth & Clin Med, S-90187 Umea, Sweden
[22] Max Planck Inst Biochem, D-82152 Martinsried, Germany
[23] Med Discovery SA, CH-1228 Plan Les Ouates, Switzerland
[24] Kantonsspital Aarau, Urol Clin, CH-5001 Aarau, Switzerland
[25] Dyax Corp, Cambridge, MA 02139 USA
[26] Univ Washington, Dept Urol, Seattle, WA 98195 USA
[27] Acad Athens, Fdn Biomed Res, Dept Biotechnol, GR-11527 Athens, Greece
关键词
cancer; evolution; hormone; inflammation; kininogen;
D O I
10.1515/BC.2006.082
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.
引用
收藏
页码:637 / 641
页数:5
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