NMR spectroscopy of laser-polarized 129Xe under continuous flow:: A method to study aqueous solutions of biomolecules

被引：31

作者：

Baumer, Daniela

Brunner, Eike

Bluemler, Peter

Zaenker, Paul Philipp

Spiess, Hans Wolfgang

机构：

[1] Univ Regensburg, Inst Biophys & Phys Biochem, D-93040 Regensburg, Germany

[2] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

[3] Res Ctr Julich, D-52425 Julich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 43期

关键词：

gas dissolution; laser polarization; lipid bicelles; NMR spectroscopy; xenon;

D O I：

10.1002/anie.200601008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Go with the flow: In many applications of NMR spectroscopy in chemistry, proper sample preparation is absolutely critical for success, in particular in biochemical and biomedical areas. For the NMR spectroscopy of laser-polarized 129Xe, an efficient and robust method for continuous flow of the gas to a NMR tube was developed. Applications to H2O, DMSO, phospholipid bicelles, and 2D exchange NMR spectroscopy are demonstrated. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7282 / 7284

页数：3

共 26 条

[1] ALBERT MS, 1994, NATURE, V370, P199, DOI 10.1038/370199a0
[2] Measurement of the 129Xe NMR chemical shift of supercritical xenon
Baumer, D
Fink, A
Brunner, E
[J]. ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS, 2003, 217 (03): : 289 - 293
[3] NMR of laser-polarized xenon in human blood
Bifone, A
Song, YQ
Seydoux, R
Taylor, RE
Goodson, BM
Pietrass, T
Budinger, TF
Navon, G
Pines, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (23) : 12932 - 12936
[4] Surface NMR using laser-polarized 129Xe under magic angle spinning conditions
Brunner, E
Seydoux, R
Haake, M
Pines, A
Reimer, JA
[J]. JOURNAL OF MAGNETIC RESONANCE, 1998, 130 (01) : 145 - 148
[5] Surface-enhanced NMR using continuous-flow laser-polarized xenon
Haake, M
Pines, A
Reimer, JA
Seydoux, R
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (48) : 11711 - 11712
[6] NMR-based biosensing with optimized delivery of polarized 129Xe to solutions
Han, SI
Garcia, S
Lowery, TJ
Ruiz, EJ
Seeley, JA
Chavez, L
King, DS
Wemmer, DE
Pines, A
[J]. ANALYTICAL CHEMISTRY, 2005, 77 (13) : 4008 - 4012
[7] XE-129 NMR-STUDY OF XENON ADSORBED ON Y ZEOLITES
ITO, T
FRAISSARD, J
[J]. JOURNAL OF CHEMICAL PHYSICS, 1982, 76 (11) : 5225 - 5229
[8] DENSITY DEPENDENCE OF XE-129 CHEMICAL SHIFTS IN MIXTURES OF XENON AND OTHER GASES
JAMESON, AK
JAMESON, CJ
GUTOWSKY, HS
[J]. JOURNAL OF CHEMICAL PHYSICS, 1970, 53 (06) : 2310 - &
[9] TEMPERATURE AND DENSITY DEPENDENCE OF XE-129 CHEMICAL-SHIFT IN XENON GAS
JAMESON, CJ
JAMESON, AK
COHEN, SM
[J]. JOURNAL OF CHEMICAL PHYSICS, 1973, 59 (08) : 4540 - 4546
[10] INVESTIGATION OF EXCHANGE PROCESSES BY 2-DIMENSIONAL NMR-SPECTROSCOPY
JEENER, J
MEIER, BH
BACHMANN, P
ERNST, RR
[J]. JOURNAL OF CHEMICAL PHYSICS, 1979, 71 (11) : 4546 - 4553

← 1 2 3 →