Self-assembly and antioxidant properties of octanoyl-6-O-ascorbic acid

被引：53

作者：

Lo Nostro, P

Capuzzi, G

Romani, A

Mulinacci, N

机构：

[1] Univ Florence, Dept Chem, I-50121 Florence, Italy

[2] Univ Florence, CSGI, I-50121 Florence, Italy

[3] Univ Florence, Dept Pharmaceut Sci, I-50121 Florence, Italy

来源：

LANGMUIR | 2000年 / 16卷 / 04期

关键词：

D O I：

10.1021/la990796j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Vitamin C acts as a powerful radical scavenger, and can be used as a convenient antioxidant agent in aqueous media. To extend its properties to nonaqueous environments, alkanoyl-6-O-ascorbic acid esters with different chain lengths were synthesized, and their micellar and antioxidant properties were investigated by surface tension, viscosity, light scattering, neutron scattering, oxygen uptake, and UV/VIS spectra. According to our results, octanoyl-ascorbic acid forms nearly spherical micelles in water solutions above a cmc of about 6 x 10(-3) mol/L at 30 degrees C, while decanoyl- and dodecanoyl-ascorbic acid are poorly soluble in water. No matter how long the hydrophobic chain is, all these esters show the same antioxidant activity as vitamin C and other natural products.

引用

页码：1744 / 1750

页数：7

共 38 条

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