Management of severe sepsis and septic shock: Challenges and recommendations

被引：39

作者：

Gullo, Antonino

Bianco, Nicola

Berlot, Giorgio

机构：

[1] Policlin Univ Hosp, Dept Anaesthesia & Intens Care, Sch Med, I-95123 Catania, Italy

[2] Cattinara Univ Hosp, Dept Perioperat Med Intens Care & Emergency, Sch Med, I-34100 Trieste, Italy

来源：

CRITICAL CARE CLINICS | 2006年 / 22卷 / 03期

关键词：

D O I：

10.1016/j.ccc.2006.03.006

中图分类号：

R4 [临床医学];

学科分类号：

1002 [临床医学]; 100602 [中西医结合临床];

摘要：

Sepsis and related aspects has become an area of active and intense research, leading to important advances for an early diagnosis and appropriate management useful to improve patient outcome. The septic response is an extremely complex cascade of events, including proinflammatory, anti-inflammatory, humoral cellular, and circulatory involvement. The pathophysiology of this syndrome, its various and changing clinical aspects, and the vast variety of therapeutic options available, not always of well-proved efficacy, make its management a goal difficult to achieve.

引用

页码：489 / +

页数：14

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