Effect of extracts from Rhodiola rosea and Rhodiola Crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles

被引:103
作者
Abidov, M [1 ]
Crendal, F
Grachev, S
Seifulla, R
Ziegenfuss, T
机构
[1] Russian Acad Nat Sci, Inst Immunopathol, Moscow, Russia
[2] IM Setchenov Med Acad, Moscow, Russia
[3] Russian Ctr Higher Athlet Educ, Moscow, Russia
关键词
ATP; mitochondria; Rhodiola rosea; Rhodiola crenulata; rosavines; salidroside;
D O I
10.1023/B:BEBM.0000020211.24779.15
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We studied the effects of oral treatment with extracts from Rhodiola rosea (50 mg/kg) and Rhodiola crenulata (50 mg/kg) roots on the duration of exhaustive swimming and ATP content in mitochondria of skeletal muscles In rats. Treatment with R. rosea extract significantly (by 24.6%) prolonged the duration of exhaustive swimming in comparison with control rats and rats treated with R. crenulata. R. rosea extract activated the synthesis or resynthesis of ATP in mitochondria and stimulated reparative energy processes after intense exercise. Experiments proved different pharmacological characteristics of R. rosea and R. crenulata: R. rosea is most effective for improving physical working capacity.
引用
收藏
页码:585 / 587
页数:3
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