Syntheses of novel hapten-protein conjugates for production of highly specific antibodies to formononetin, daidzein and genistein

被引：39

作者：

Le Houérou, C

Bennetau-Pelissero, C

Lamothe, V

Le Menn, F

Babin, P

Bennetau, B

机构：

[1] Univ Bordeaux 1, Lab Biol Reprod Poissons, F-33405 Talence, France

[2] Univ Bordeaux 1, Chim Organ & Organomet Lab, CNRS, UMR 5802, F-33405 Talence, France

[3] ENITA Bordeaux, F-33175 Gradignan, France

[4] Univ Bordeaux 2, Lab Pharm Chim, F-33000 Bordeaux, France

来源：

TETRAHEDRON | 2000年 / 56卷 / 02期

关键词：

hapten-protein conjugates; antibodies; isoflavones;

D O I：

10.1016/S0040-4020(99)00993-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of novel hapten-carrier protein conjugates are described. Isoflavones functionalised in C2 were coupled to bovine serum albumin or swine thyroglobulin. The antibodies obtained were used for the development of ELISAs (enzyme-linked immunosorbent assays) to measure the three isoflavones with IC50 ranging from 15.6 to 100 ng/mL. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：295 / 301

页数：7

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