Proteome chips for whole-organism assays

被引：45

作者：

Kung, Li A. ^{[1
]}

Snyder, Michael ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06511 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 08期

关键词：

ORFEOME VERSION 1.1; GENE-EXPRESSION; GLOBAL ANALYSIS; YEAST PROTEOME; MICROARRAY; ANTIBODY; PROTEINS; IDENTIFICATION; PURIFICATION; DATABASES;

D O I：

10.1038/nrm1941

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Over the past 5 years, protein-chip technology has emerged as a useful tool for the study of many kinds of protein interactions and biochemical activities. The construction of Saccharomyces cerevisiae whole-proteome arrays has enabled further studies of such interactions in a proteome-wide context. Here, we explore some of the recent advances that have been made at the '-omic' level using protein microarrays.

引用

页码：617 / 622

页数：6

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