In vivo diffusion tensor imaging of rat spinal cord at 7 T

被引：49

作者：

Elshafiey, I ^{[1
]}

Bilgen, M ^{[1
]}

He, RJ ^{[1
]}

Narayana, PA ^{[1
]}

机构：

[1] Univ Texas, Sch Med, Dept Radiol, Houston, TX 77030 USA

来源：

MAGNETIC RESONANCE IMAGING | 2002年 / 20卷 / 03期

关键词：

spinal cord; implantable coil; diffusion tensor imaging; diffusion anisotropy; biexponential diffusion; fast and slow diffusion;

D O I：

10.1016/S0730-725X(02)00493-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

In vivo diffusion tensor imaging of normal rat spinal cord was performed using a multi-segmented, blipped EPI sequence at 7 T field strength. At high diffusion weighting, the signal exhibited a non-monoexponential decay that was fitted to a biexponential function, associated with the fast and slow components of diffusion in the cord tissue, using a nonlinear regression analysis along with a constrained optimization procedure. From the measured tensors, the eigenvalues and the maps of invariant scalar measures (fractional anisotropy, relative anisotropy, volume ratio, and trace) were calculated and analyzed statistically. The results were combined to quantitatively characterize the anisotropic properties of the fast and slow diffusions in white- and gray matter of live spinal cords. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：243 / 247

页数：5

共 35 条

[1] Alexander AL, 2000, MAGNET RESON MED, V44, P283, DOI 10.1002/1522-2594(200008)44:2<283::AID-MRM16>3.0.CO
[2] 2-V
[3] Assaf Y, 2000, MAGNET RESON MED, V43, P191, DOI 10.1002/(SICI)1522-2594(200002)43:2<191::AID-MRM5>3.0.CO
[4] 2-B
[5] MR DIFFUSION TENSOR SPECTROSCOPY AND IMAGING
BASSER, PJ
MATTIELLO, J
LEBIHAN, D
[J]. BIOPHYSICAL JOURNAL, 1994, 66 (01) : 259 - 267
[6] Correction of eddy current-induced artefacts in diffusion tensor imaging using iterative cross-correlation
Bastin, ME
[J]. MAGNETIC RESONANCE IMAGING, 1999, 17 (07) : 1011 - 1024
[7] In vivo magnetic resonance microscopy of rat spinal cord at 7 T using implantable RF coils
Bilgen, M
Elshafiey, I
Narayana, PA
[J]. MAGNETIC RESONANCE IN MEDICINE, 2001, 46 (06) : 1250 - 1253
[8] BOSSART EL, 1999, P 7 ANN M ISMRM PHIL, P328
[9] BOSSART EL, 2000, P 8 ANN M ISMRM DENV, P763
[10] Clark CA, 2000, MAGN RESON MED, V44, P852, DOI 10.1002/1522-2594(200012)44:6<852::AID-MRM5>3.0.CO

← 1 2 3 4 →