Asymmetric Strecker reactions of ketimines catalysed by titanium-based complexes

被引:76
作者
Byrne, JJ [1 ]
Chavarot, M [1 ]
Chavant, PY [1 ]
Vallée, Y [1 ]
机构
[1] Univ Grenoble 1, CNRS, LEDSS, F-38041 Grenoble, France
关键词
D O I
10.1016/S0040-4039(99)02215-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The asymmetric addition of TMSCN to a ketimine has been achieved by use of catalytic quantities of chiral titanium(IV) complexes. Fast conversions together with enantiomeric excesses as high as 59% have been achieved. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:873 / 876
页数:4
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