Detection and quantification of magnetically labeled cells by cellular MRI

被引：141

作者：

Liu, Wei ^{[1
,2
]}

Frank, Joseph A. ^{[1
]}

机构：

[1] NIH, Expt Neuroimaging Sect, Lab Diagnost Radiol Res, Bethesda, MD 20892 USA

[2] Philips Res N Amer, Briarcliff Manor, NY 10510 USA

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2009年 / 70卷 / 02期

基金：

美国国家卫生研究院;

关键词：

MRI; Cell labeling; SPIO nanoparticles; Gadolinium; Perfluorocarbon; IRON-OXIDE NANOPARTICLES; STATIC DEPHASING REGIME; TARGETING GENE DELIVERY; MESENCHYMAL STEM-CELLS; IN-VIVO TRACKING; CONTRAST AGENT; SUPERPARAMAGNETIC NANOPARTICLES; RESONANCE TRACKING; FIELD INHOMOGENEITIES; TRANSFECTION AGENTS;

D O I：

10.1016/j.ejrad.2008.09.021

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Labeling cells with superparamagnetic iron oxide (SPIO) nanoparticles, paramagnetic contrast agent (gadolinium) or perfluorocarbons allows for the possibility of tracking single or clusters of labeled cells within target tissues following either direct implantation or intravenous injection. This review summarizes the practical issues regarding detection and quantification of magnetically labeled cells with various MRI contrast agents with a focus on SPIO nanoparticles. Published by Elsevier Ireland Ltd.

引用

页码：258 / 264

页数：7

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