Notch around the clock

被引:53
作者
Pourquié, O [1 ]
机构
[1] Univ Mediterranee, AP Marseille, INSERM, CNRS,IBDM,LGPD, F-13288 Marseille 09, France
基金
澳大利亚研究理事会;
关键词
D O I
10.1016/S0959-437X(99)00011-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The establishment of a segmental pattern within the vertebrate body plan is achieved during embryogenesis by the somitogenesis process. Two molecular systems have been implicated in this phenomenon: a molecular clock linked to vertebrate segmentation and the Notch signalling pathway. Rhythmic expression of the Lunatic Fringe gene in the presomitic mesoderm has now provided a link between these two systems.
引用
收藏
页码:559 / 565
页数:7
相关论文
共 44 条
  • [31] 2-3
  • [32] Fringe modulates notch ligand interactions
    Panin, VM
    Papayannopoulos, V
    Wilson, R
    Irvine, KD
    [J]. NATURE, 1997, 387 (6636) : 908 - 912
  • [33] Dorsal-ventral signaling in the Drosophila eye
    Papayannopoulos, V
    Tomlinson, A
    Panin, VM
    Rauskolb, C
    Irvine, KD
    [J]. SCIENCE, 1998, 281 (5385) : 2031 - 2034
  • [34] Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement
    Saga, Y
    [J]. MECHANISMS OF DEVELOPMENT, 1998, 75 (1-2) : 53 - 66
  • [35] Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation
    Saga, Y
    Hata, N
    Koseki, H
    Taketo, MM
    [J]. GENES & DEVELOPMENT, 1997, 11 (14) : 1827 - 1839
  • [36] 2 MAMMALIAN HELIX LOOP HELIX FACTORS STRUCTURALLY RELATED TO DROSOPHILA HAIRY AND ENHANCER OF SPLIT
    SASAI, Y
    KAGEYAMA, R
    TAGAWA, Y
    SHIGEMOTO, R
    NAKANISHI, S
    [J]. GENES & DEVELOPMENT, 1992, 6 (12B) : 2620 - 2634
  • [37] Sparrow DB, 1998, DEVELOPMENT, V125, P2041
  • [38] Stern CD, 1998, BIOESSAYS, V20, P528, DOI 10.1002/(SICI)1521-1878(199807)20:7<528::AID-BIES2>3.0.CO
  • [39] 2-G
  • [40] TAKEBAYASHI K, 1994, J BIOL CHEM, V269, P5150