Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia

被引：118

作者：

Bekkering, Siroon ^{[1
,2
,3
]}

Stiekema, Lotte C. A. ^{[3
]}

Moens, Sophie Bernelot ^{[3
]}

Verweij, Simone L. ^{[3
]}

Novakovic, Boris ^{[4
]}

Prange, Koen ^{[5
]}

Versloot, Miranda ^{[3
]}

van Lennep, Jeanine E. Roeters ^{[6
]}

Stunnenberg, Henk ^{[7
]}

de Winther, Menno ^{[5
,8
]}

Stroes, Erik S. G. ^{[3
]}

Joosten, Leo A. B. ^{[1
,2
,9
]}

Netea, Mihai G. ^{[1
,2
,10
]}

Riksen, Niels P. ^{[1
,2
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Internal Med, NL-6525 GA Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, RIMLS, Med Ctr, NL-6525 GA Nijmegen, Netherlands

[3] Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

[4] Royal Childrens Hosp, Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia

[5] Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Med Biochem, Expt Vasc Biol, NL-1105 AZ Amsterdam, Netherlands

[6] Erasmus Univ, Med Ctr, Dept Internal Med, NL-3015 GD Rotterdam, Netherlands

[7] Radboud Univ Nijmegen, Med Ctr, RIMLS, Dept Mol Biol, NL-6525 GA Nijmegen, Netherlands

[8] Inst Cardiovasc Prevent IPEK, D-80336 Munich, Germany

[9] Iuliu Hatieganu Univ Med & Pharm, Dept Med Genet, Cluj Napoca 400000, Romania

[10] Univ Bonn, Dept Immunol & Metab, Life & Med Sci Inst LIMES, D-53115 Bonn, Germany

来源：

CELL METABOLISM | 2019年 / 30卷 / 01期

基金：

英国医学研究理事会; 欧盟地平线“2020”; 澳大利亚国家健康与医学研究理事会;

关键词：

D O I：

10.1016/j.cmet.2019.05.014

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

引用

页码：1 / 2

页数：2

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