Camptothecine from callus cultures of Nothapodytes foetida

被引：46

作者：

Ciddi, V ^{[1
]}

Shuler, ML

机构：

[1] Cornell Univ, Sch Chem Engn, Ithaca, NY 14853 USA

[2] Kakatiya Univ, Fac Pharmaceut Sci, Warangal 506009, Andhra Pradesh, India

来源：

BIOTECHNOLOGY LETTERS | 2000年 / 22卷 / 02期

关键词：

camptothecine; 9-methoxy-camptothecine; plant tissue cultures; Nothapodytes foetida;

D O I：

10.1023/A:1005666223003

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Callus cultures were established from excised embryos of Nothapodytes foetida on Murashige and Skoog medium supplemented with picloram (2 mg l(-1)) and 3% (w/v) sucrose. The embryos developed into callus after 4 weeks of incubation at 25 +/- 2 degrees C in dark. The cultures produced camptothecine and 9-methoxy-camptothecine as determined by TLC, UV, HPLC, electron spray mass spectral analysis.

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收藏

页码：129 / 132

页数：4

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