Stability and stoichiometry of some binary fluorophore-cyclodextrin complexes

被引：10

作者：

D'Anna, F ^{[1
]}

Riela, S ^{[1
]}

Lo Meo, P ^{[1
]}

Noto, R ^{[1
]}

机构：

[1] Univ Palermo, Dipartimento Chim Organ E Paterno, I-90128 Palermo, Italy

来源：

TETRAHEDRON | 2004年 / 60卷 / 25期

关键词：

cyclodextrins; binary complexes; fluorescence;

D O I：

10.1016/j.tet.2004.04.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The stability and stoichiometric ratio of binary complexes among five fluorophores and P-cyclodextrin (P-CD) or heptakis-(6-amino-6-deoxy)-beta-cyclodextrin (am-beta-CD) were determined by means of fluorescence measurements in borate buffer at pH=8.0 and 9.0. Structure of both host and guest affected the characteristics of the binary complexes. Pyrene and anthraquinone formed a 1:2 (fluorophore: cyclodextrin) complex with both cyclodextrins. Xanthone formed 1: 1 complex with P-CD and 1:2 complex with am-beta-CD. A more defined behaviour was observed for crysene. In fact, both stoichiometric different complexes were detected with both hosts. Only 1: 1 complexes were observed for antracene. The complex stability was affected by the pH of the solution. MM2 calculations were performed in order to gain information about the forces working on the formation of complexes. (C) 2004 Elsevier Ltd. All rights reserved.

引用

收藏

页码：5309 / 5314

页数：6

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