Staphylococcal vaccines and immunotherapy: to dream the impossible dream?

被引：74

作者：

Projan, Steven J.

Nesin, Mirjana

Dunman, Paul M.

机构：

[1] Wyeth Res, Cambridge, MA 02140 USA

[2] Boston Univ, Sch Med, Boston, MA 02118 USA

[3] Univ Nebraska, Med Ctr, Omaha, NE USA

来源：

CURRENT OPINION IN PHARMACOLOGY | 2006年 / 6卷 / 05期

关键词：

D O I：

10.1016/j.coph.2006.04.005

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Staphylococcal infections not only remain an important cause of morbidity and mortality in both the community and the clinic, but the emergence of a global pandemic of community-associated methicillin-resistant Staphylococcus aureus, involving what purports to be a more virulent strain of this organism, has also led several in the infectious disease community to call for improved disease prevention strategies (in addition to novel therapeutics) in what could be thought of as the microbiological version of pre-emption. In this case, Staphylococcus aureus possesses 'weapons of mass destruction' and appears to be using them effectively as part of anti-immunization insurgency.

引用

收藏

页码：473 / 479

页数：7

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