Genome research and evolution in trypanosomes

被引：20

作者：

Donelson, JE ^{[1
]}

机构：

[1] HOWARD HUGHES MED INST,IOWA CITY,IA 52242

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0959-437X(96)80023-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Trypanosoma brucei and Trypanosoma cruzi cause different human diseases. As strategies for immune evasion, T. brucei undergoes antigenic variation whereas T. cruzi becomes an intracellular organism. This fundamental difference is reflected by major differences in their genome organizations. Recent comparisons of their gene sequences indicate that these two trypanosome species are highly divergent evolutionarily.

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页码：699 / 703

页数：5

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