Studies on new antitumor antibiotics, leptofuranins A, B, C and D .2. Physicochemical properties and structure elucidation

被引：27

作者：

Hayakawa, Y

Sohda, KY

Seto, H

机构：

[1] Inst. of Molec. and Cell. Biosci., University of Tokyo, Bunkyo-ku

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 10期

关键词：

D O I：

10.7164/antibiotics.49.980

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structures of new antitumor antibiotics, leptofuranins A, B, C and D were elucidated to be as shown in Fig. 1 by NMR spectral analysis including a variety of two-dimensional techniques. The leptofuranins are novel leptomycin-related substances containing a tetrahydrofuran ring. Leptofuranins C and D were revealed to be in tautomeric isomerism and their relative stereochemistries were analyzed by NOESY experiments.

引用

页码：980 / 984

页数：5

共 8 条

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