Prevalence of Helicobacter pylori vacA and cagA genotypes in Ethiopian dyspeptic patients

被引：22

作者：

Asrat, D

Nilsson, I

Mengistu, Y

Kassa, E

Ashenafi, S

Ayenew, K

Wadström, T

Abu-Al-Soud, W

机构：

[1] Lund Univ, Dept Med Microbiol Dermatol & Infect, SE-22362 Lund, Sweden

[2] Armauer Hansen Res Inst, Addis Ababa, Ethiopia

[3] Univ Addis Ababa, Fac Med, Dept Pathol, Addis Ababa, Ethiopia

[4] Univ Addis Ababa, Fac Med, Dept Internal Med, Addis Ababa, Ethiopia

[5] Univ Addis Ababa, Fac Med, Dept Med Microbiol Immunol & Parasitol, Addis Ababa, Ethiopia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2004年 / 42卷 / 06期

关键词：

D O I：

10.1128/JCM.42.6.2682-2684.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

A total of 300 gastric biopsy samples and 50 Helicobacter pylori isolates were collected from Ethiopian adult dyspeptic patients. The vacA and cagA genes were detected in 90 and 79% of biopsy specimens, respectively, and in 100 and 87% of clinical isolates, respectively. Both genes were detected in 84% of the gastric biopsy samples and in 87% of the clinical isolates. Among vacA genotypes, the s1/m1 genotype was the most common in gastric biopsy samples (48%). The vacA and cagA positive H. pylori strains were detected to a higher degree in patients with chronic active gastritis (71%) than patients with other histopathological findings (29%) (P < 0.05).

引用

收藏

页码：2682 / 2684

页数：3

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