Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in chicken

被引：271

作者：

Kong, XF ^{[1
]}

Hu, YL ^{[1
]}

Rui, R ^{[1
]}

Wang, DY ^{[1
]}

Li, XG ^{[1
]}

机构：

[1] Nanjing Arg Univ, Coll Vet Med, Inst Tradit Chinese Vet Med, Jiangsu 210095, Peru

来源：

INTERNATIONAL IMMUNOPHARMACOLOGY | 2004年 / 4卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Chinese herbal medicinal ingredients; peripheral lymphocyte proliferation; serum antibody titer;

D O I：

10.1016/j.intimp.2004.03.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The purpose of these experiments is to study the effects of Chinese herbal medicinal ingredients (CHMIs) on peripheral lymphocyte proliferation and serum antibody titer in chicken vaccinated with Newcastle disease (ND) vaccine. Nine CHMIs were chosen for the experiments. Astragalus polysaccharide (APS), Isatis root polysaccharide (IRPS), Epimedium flavone (EF), Propolis flavone (PF), Astragalosides (AS) and Ginsenosides (GS) could promote lymphocyte proliferation and antibody titer, while Epimedium polysaccharide (EPS) mainly stimulated cellular immune responses. Chinese angelica polysaccharide (CAPS) and Propolis polysaccharide (PPS) exerted weaker effects on promoting immune responses. APS, IRPS, PPS and PF in promoting lymphocyte proliferation, and IRPS, PPS, EF and PF in promoting humoral immunity in higher dose were significantly stronger than in lower dose. Our results indicated that almost all of the nine CHMIs could promote both humoral and cellular immune responses and would be expected as the component drug of a new-type immunopotentiator. (C) 2004 Published by Elsevier B.V.

引用

页码：975 / 982

页数：8

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