Kinetic and safety assessment for salicylic acid nitration by nitric acid/acetic acid system

被引：33

作者：

Andreozzi, R.

Caprio, V.

Di Somma, I.

Sanchirico, R.

机构：

[1] Univ Naples Federico II, I-80125 Naples, Italy

[2] Ist Ric Combust, CNR, I-80125 Naples, Italy

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2006年 / 134卷 / 1-3期

关键词：

nitration; salicylic acid; thermal explosion; adiabatic calorimetry; modelling;

D O I：

10.1016/j.jhazmat.2005.10.037

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The nitration process of salicylic acid for the production of the important intermediate 5-nitrosalicylic acid is studied from thermokinetic and safety points of view. Investigations carried out by considering, as process deviations, the loss of the thermal control point out the possibility of runaway phenomena due to the occurrence of polynitration reactions. Isothermal experiments are carried out in various conditions to assess the involved reaction network and reaction kinetics. (c) 2005 Elsevier B.V All rights reserved.

引用

页码：1 / 7

页数：7

共 15 条

[1] (S)-Nitroxycamitine nitrate production from (S)-carnitine by using acetic anhydride/nitric acid/acetic acid mixtures:: safety assessment [J].