Cholestatic Liver Diseases: A Primer for Generalists and Subspecialists

被引:38
作者
Hilscher, Moira B. [1 ]
Kamath, Patrick S. [1 ]
Eaton, John E. [1 ]
机构
[1] Mayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
关键词
PRIMARY BILIARY-CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PLACEBO-CONTROLLED TRIAL; INTRAHEPATIC CHOLESTASIS; URSODEOXYCHOLIC ACID; CLINICAL-FEATURES; OBETICHOLIC ACID; KASAI OPERATION; ORGANIC-ANIONS; BILE-ACIDS;
D O I
10.1016/j.mayocp.2020.01.015
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Cholestasis describes impairment in bile formation or flow which can manifest clinically with fatigue, pruritus, and jaundice. The differential diagnosis of cholestatic liver diseases is broad, and the etiologies of cholestasis vary in the anatomical location of the defect and acuity of presentation. Cholestasis may occur in a variety of clinical scenarios. Therefore, it is important for a diverse audience with varied clinical practices to have a basic understanding of manifestations of cholestatic liver diseases. (C) 2020 Mayo Foundation for Medical Education and Research
引用
收藏
页码:2263 / 2279
页数:17
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