Treatment with leuprolide acetate and hormonal add-back for up to 10 years in stage IV endometriosis patients with chronic pelvic pain

被引:45
作者
Bedaiwy, Mohamed A.
Casper, Robert F. [1 ]
机构
[1] Univ Toronto, Div Reprod Sci, Dept Obstet & Gynecol, Toronto, ON M5G 1X5, Canada
[2] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
关键词
D O I
10.1016/j.fertnstert.2005.12.030
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
This pilot study examined the effect of a low-dose E and pulsed progestogen hormone therapy (HT) regimen for add-back during long-term GnRH-agonist therapy on bone mineral density (BMD) in five patients with stage IV endometriosis. Bone mineral density was stable after initiation of HT for the entire follow-up period (up to 10 years). One patient stopped her treatment on two occasions to conceive and was successful each time with delivery of a normal baby. No patient had return of pelvic pain after HT add-back.
引用
收藏
页码:220 / 222
页数:3
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