Tissue engineering efforts are currently being undertaken for every type of tissue and organ within the urinary system. Most of the effort expended to engineer genitourinary tissues has occurred within the past decade. Tissue engineering techniques require a cell culture facility designed for human application. Personnel who have mastered the techniques of cell harvest, culture, and expansion in addition to polymer design are essential for the successful application of this technology. Before these engineering techniques can be applied to humans, further studies need to be performed in many of the tissues described. Recent progress suggests that engineered urologic tissues and cell therapy may have clinical applicability.