Stabilized porous phospholipid nanoshells

被引:16
作者
Cheng, Zhiliang [1 ]
D'Ambruoso, Gemma D. [1 ]
Aspinwall, Craig A. [1 ]
机构
[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA
关键词
D O I
10.1021/la061542i
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemically stabilized, porous phospholipid nanoshells (PPNs) were prepared via copolymerization of reactive monomers with unilamellar bis-Sorbyl phosphatidylcholine vesicles. The resulting PPN vesicular assemblies possess a highly porous membrane structure that allows passage of small molecules, which can react with encapsulated proteins and reporters. The unique combination of membrane stability and porosity will prove useful for preparing nanometer-sized sensor, container, and reactor platforms stable in harsh chemical and biological environments.
引用
收藏
页码:9507 / 9511
页数:5
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