Baseline correction by improved iterative polynomial fitting with automatic threshold

被引:167
作者
Gan, Feng [1 ]
Ruan, Guihua [1 ]
Mo, Jinyuan [1 ]
机构
[1] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
data processing; baseline correction; iterative polynomial fitting; automatic threshold;
D O I
10.1016/j.chemolab.2005.08.009
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
An iterative polynomial fitting method is proposed for the estimate of the baseline of chemical signal. The new method generates automatic thresholds by comparing the chemical signal with the calculated signal from polynomial fitting in the iterative processes. The signal peaks are cut out consecutively in the iterative processes so the polynomial fitting will finally give a good estimation of the baseline. Simulated data and real data from capillary electrophoresis experiment are used to demonstrate the feasibility of the proposed method. (c) 2005 Elsevier B.V All rights reserved.
引用
收藏
页码:59 / 65
页数:7
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