Genetic research and health disparities

被引:184
作者
Sankar, P
Cho, MK
Condit, CM
Hunt, LM
Koenig, B
Marshall, P
Lee, SSJ
Spicer, P
机构
[1] Univ Penn, Ctr Bioeth, Sch Med, Philadelphia, PA 19104 USA
[2] Stanford Univ, Ctr Biomed Eth, Dept Neurol & Neurol Sci, Palo Alto, CA 94304 USA
[3] Univ Georgia, Dept Speech Commun, Athens, GA 30602 USA
[4] Michigan State Univ, Dept Anthropol, E Lansing, MI 48824 USA
[5] Case Western Reserve Univ, Sch Med, Dept Bioeth, Cleveland, OH USA
[6] Univ Colorado, Sch Med, Denver, CO USA
来源
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2004年 / 291卷 / 24期
关键词
D O I
10.1001/jama.291.24.2985
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Alleviating health disparities in the United States is a goal with broad support. Medical research undertaken to achieve this goal typically adopts the well-established perspective that racial discrimination and poverty are the major contributors to unequal health status. However, the suggestion is increasingly made that genetic research also has a significant role to play in alleviating this problem, which likely overstates the importance of genetics as a factor in health disparities. Overemphasis on genetics as a major explanatory factor in health disparities could lead researchers to miss factors that contribute to disparities more substantially and may also reinforce racial stereotyping, which may contribute to disparities in the first place. Arguments that promote genetics research as a way to help alleviate health disparities are augmented by several factors, including research funding initiatives and the distinct demographic patterns of health disparities in the United States.
引用
收藏
页码:2985 / 2989
页数:5
相关论文
共 67 条
[1]  
Alexander GR, 1999, PAEDIATR PERINAT EP, V13, P205
[2]  
Andrews R M, 2000, Ethn Dis, V10, P384
[3]   Fatty acids, diet, and body indices of type II diabetic American whites and blacks and Ghanaians [J].
Banini, AE ;
Allen, JC ;
Allen, HG ;
Boyd, LC ;
Lartey, A .
NUTRITION, 2003, 19 (09) :722-726
[4]   Exposure to indoor pesticides during pregnancy in a multiethnic, urban cohort [J].
Berkowitz, GS ;
Obel, J ;
Deych, E ;
Lapinski, R ;
Godbold, J ;
Liu, ZS ;
Landrigan, PJ ;
Wolff, MS .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2003, 111 (01) :79-84
[5]   Informed lay preferences for delivery of racially varied pharmacogenomics [J].
Bevan, JL ;
Lynch, JA ;
Dubriwny, TN ;
Harris, TM ;
Achter, PJ ;
Reeder, AL ;
Condit, CM .
GENETICS IN MEDICINE, 2003, 5 (05) :393-399
[6]   Neuropsychological effects of ethylene dichloride exposure [J].
Bowler, RM ;
Gysens, S ;
Hartney, C .
NEUROTOXICOLOGY, 2003, 24 (4-5) :553-562
[7]   Hereditary prostate cancer: Clinical aspects [J].
Bratt, O .
JOURNAL OF UROLOGY, 2002, 168 (03) :906-913
[8]   Do the print media "hype" genetic research? A comparison of newspaper stories and peer-reviewed research papers [J].
Bubela, TM ;
Caulfield, TA .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 170 (09) :1399-1407
[9]   The importance of race and ethnic background in biomedical research and clinical practice [J].
Burchard, EG ;
Ziv, E ;
Coyle, N ;
Gomez, SL ;
Tang, H ;
Karter, AJ ;
Mountain, JL ;
Pérez-Stable, EJ ;
Sheppard, D ;
Risch, N .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (12) :1170-1175
[10]   RISK-FACTORS FOR ASTHMA IN INNER-CITY CHILDREN [J].
CALL, RS ;
SMITH, TF ;
MORRIS, E ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
JOURNAL OF PEDIATRICS, 1992, 121 (06) :862-866