The many functions of SMC proteins in chromosome dynamics

被引：132

作者：

Jessberger, R ^{[1
]}

机构：

[1] Mt Sinai Sch Med, Carl C Icahn Inst Gene Therapy & Mol Med, New York, NY 10029 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 10期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm930

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of the structural maintenance of chromosomes (SMC) family share a characteristic design and configuration of protein domains that provides the molecular basis for the various functions of this family in chromosome dynamics. SMC proteins have a role in chromosome condensation, sister-chromatid cohesion, DNA repair and recombination, and gene dosage compensation, and they function in somatic and meiotic cells. As more is learned about how their unique design affects their function, a picture of a dynamic and varied protein family is emerging.

引用

页码：767 / 778

页数：12

共 106 条

[71] The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents
Morishita, T
Tsutsui, Y
Iwasaki, H
Shinagawa, H
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (10) : 3537 - 3548
[72] Disseminating the genome: Joining, resolving, and separating sister chromatids during mitosis and meiosis
Nasmyth, K
[J]. ANNUAL REVIEW OF GENETICS, 2001, 35 : 673 - 745
[73] A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction
Pasierbek, P
Jantsch, M
Melcher, M
Schleiffer, A
Schweizer, D
Loidl, J
[J]. GENES & DEVELOPMENT, 2001, 15 (11) : 1349 - 1360
[74] A meiotic chromosomal core consisting of cohesin complex proteins recruits DNA recombination proteins and promotes synapsis in the absence of an axial element in mammalian meiotic cells
Pelttari, J
Hoja, MR
Yuan, L
Liu, JG
Brundell, E
Moens, P
Santucci-Darmanin, S
Jessberger, R
Barbero, JL
Heyting, C
Höög, C
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (16) : 5667 - 5677
[75] THE SMC FAMILY - NOVEL MOTOR PROTEINS FOR CHROMOSOME CONDENSATION
PETERSON, CL
[J]. CELL, 1994, 79 (03) : 389 - 392
[76] Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I
Prieto, I
Suja, JA
Pezzi, N
Kremer, L
Martinez, C
Rufas, JS
Barbero, JL
[J]. NATURE CELL BIOLOGY, 2001, 3 (08) : 761 - 766
[77] Novel meiosis-specific isoform of mammalian SMC1
Revenkova, E
Eijpe, M
Heyting, C
Gross, B
Jessberger, R
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (20) : 6984 - 6998
[78] SCII - AN ABUNDANT CHROMOSOME SCAFFOLD PROTEIN IS A MEMBER OF A FAMILY OF PUTATIVE ATPASES WITH AN UNUSUAL PREDICTED TERTIARY STRUCTURE
SAITOH, N
GOLDBERG, IG
WOOD, ER
EARNSHAW, WC
[J]. JOURNAL OF CELL BIOLOGY, 1994, 127 (02) : 303 - 318
[79] FISSION YEAST CUT3 AND CUT14, MEMBERS OF A UBIQUITOUS PROTEIN FAMILY, ARE REQUIRED FOR CHROMOSOME CONDENSATION AND SEGREGATION IN MITOSIS
SAKA, Y
SUTANI, T
YAMASHITA, Y
SAITOH, S
TAKEUCHI, M
NAKASEKO, Y
YANAGIDA, M
[J]. EMBO JOURNAL, 1994, 13 (20) : 4938 - 4952
[80] A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation
Schmiesing, JA
Gregson, HC
Zhou, S
Yokomori, K
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (18) : 6996 - 7006

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