Membrane guanylyl cyclase receptors: an update

被引：87

作者：

Garbers, David L. ^{[1
]}

Chrisman, Ted D.

Wiegn, Phi

Katafuchi, Takeshi

Albanesi, Joseph P.

Bielinski, Vincent

Barylko, Barbara

Redfield, Margaret M.

Burnett, John C., Jr.

机构：

[1] Univ Texas, SW Med Ctr, Dept Pharmacol, Howard Hughes Med Inst,Cecil H & Ida Green Ctr Re, Dallas, TX 75390 USA

[2] Univ Texas, SW Med Ctr, Div Cardiol, Dept Internal Med, Dallas, TX 75390 USA

[3] Mayo Clin & Mayo Fdn, Cardiorenal Res Lab, Div Cardiovasc Dis, Rochester, MN 55905 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2006年 / 17卷 / 06期

关键词：

D O I：

10.1016/j.tem.2006.06.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent studies have demonstrated key roles for several membrane guanylyl cyclase receptors in the regulation of cell hyperplasia, hypertrophy, migration and extracellular matrix production, all of which having an impact on clinically relevant diseases, including tissue remodeling after injury. Additionally, cell differentiation, and even tumor progression, can be profoundly influenced by one or more of these receptors. Some of these receptors also mediate important communication between the heart and intestine, and the kidney to regulate blood volume and Na+ balance.

引用

页码：251 / 258

页数：8

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