Conversion of berberine into berberrubine by selective demethylation under microwave irradiation

被引:26
作者
Das, B [1 ]
Srinivas, KVNS [1 ]
机构
[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India
关键词
Flavonoids; -; Irradiation;
D O I
10.1081/SCC-120012993
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Berberine, a natural alkaloid, underwent selective demethylation under microwave irradiation to form an important bioactive compound, berberrubine in excellent yield.
引用
收藏
页码:3027 / 3029
页数:3
相关论文
共 8 条
[1]  
BUCKINGHAM J, 1994, DICT NATURAL PRODUCT, V1, P640
[2]   Two efficient methods for the conversion of camptothecin to mappicine ketone, an antiviral lead compound [J].
Das, B ;
Madhusudhan, P ;
Kashinatham, A .
TETRAHEDRON LETTERS, 1998, 39 (5-6) :431-432
[3]   Regioselective reduction of the α,β-double bond of some naturally occurring dienamides using NaBH4/I2 system [J].
Das, B ;
Kashinatham, A ;
Madhusudhan, P .
TETRAHEDRON LETTERS, 1998, 39 (07) :677-678
[4]   Treatment of berberine with indium [J].
Das, B ;
Srinivas, KVNS .
SYNTHETIC COMMUNICATIONS, 2001, 31 (12) :1815-1817
[5]   Synthetic studies on natural products, part V - Chemical and biochemical modifications of parthenin [J].
Das, B ;
Venkataiah, B ;
Kashinatham, A .
TETRAHEDRON, 1999, 55 (21) :6585-6594
[6]  
DAS B, 2000, UNPUB J CHEM RES S
[7]  
GHARBO SA, 1973, LLOYDIA, V36, P349
[8]  
SHAMMA M, 1978, LLOYDIA, V41, P169