mRNA localization: motile RNA, asymmetric anchors

被引：13

作者：

Bloom, K ^{[1
]}

Beach, DL ^{[1
]}

机构：

[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 1999年 / 2卷 / 06期

关键词：

D O I：

10.1016/S1369-5274(99)00029-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Techniques to label mRNA with green fluorescent protein (GFP) have provided the first real-time images of RNA motility in live yeast cells. Genetic screens for factors responsible for mRNA asymmetry (e.g. SHE genes) in yeast identified type V myosin among other proteins. Analysis of mRNA movement in various she mutants revealed the role of motor proteins in long-range transport, factors for particle formation, and cortical anchors for docking the mRNA.

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页码：604 / 609

页数：6

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