The exclusivity of multivalency in dynamic covalent processes

被引:63
作者
Badjic, JD
Cantrill, SJ
Grubbs, RH [1 ]
Guidry, EN
Orenes, R
Stoddart, JF
机构
[1] CALTECH, Arnold & Mabel Beckman Lab Chem Synth, Div Chem & Chem Engn, Pasadena, CA 91125 USA
[2] Univ Calif Los Angeles, Calif Nanosyst Inst, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
关键词
metathesis; molecular recognition; NMR spectroscopy; supramolecular chemistry;
D O I
10.1002/anie.200453963
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Less is more: It is much less efficient to synthesize both components of a multivalent recognition site separately than it is to use one multivalent component to act as a template for the catalytically orchestrated construction of the other component, as demonstrated by the formation of the mechanically interlocked, triply threaded molecular bundle shown. The situation is reiniscent of nature.
引用
收藏
页码:3273 / 3278
页数:6
相关论文
共 65 条
  • [1] High-avidity, low-affinity multivalent interactions and the block to polyspermy in Xenopus laevis
    Arranz-Plaza, E
    Tracy, AS
    Siriwardena, A
    Pierce, JM
    Boons, GJ
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (44) : 13035 - 13046
  • [2] DIALKYLAMMONIUM ION CROWN-ETHER COMPLEXES - THE FORERUNNERS OF A NEW FAMILY OF INTERLOCKED MOLECULES
    ASHTON, PR
    CAMPBELL, PJ
    CHRYSTAL, EJT
    GLINK, PT
    MENZER, S
    PHILP, D
    SPENCER, N
    STODDART, JF
    TASKER, PA
    WILLIAMS, DJ
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (17): : 1865 - 1869
  • [3] Pseudorotaxanes formed between secondary dialkylammonium salts and crown ethers
    Ashton, PR
    Chrystal, EJT
    Glink, PT
    Menzer, S
    Schiavo, C
    Spencer, N
    Stoddart, JF
    Tasker, PA
    White, AJP
    Williams, DJ
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 1996, 2 (06) : 709 - 728
  • [4] ASHTON PR, 1995, ANGEW CHEM, V107, P1997
  • [5] A mechanically interlocked bundle
    Badjic, JD
    Balzani, V
    Credi, A
    Lowe, JN
    Silvi, S
    Stoddart, JF
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2004, 10 (08) : 1926 - 1935
  • [6] Can multivalency be expressed kinetically? The answer is yes
    Badjic, JD
    Cantrill, SJ
    Stoddart, JF
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (08) : 2288 - 2289
  • [7] BALZAI V, 2003, MOL DEVICES MACHINES
  • [8] Controlling multivalent interactions in triply-threaded two-component superbundles
    Balzani, V
    Clemente-León, M
    Credi, A
    Lowe, JN
    Badjic, JD
    Stoddart, JF
    Williams, DJ
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (21) : 5348 - 5360
  • [9] Balzani V, 2000, ANGEW CHEM INT EDIT, V39, P3348, DOI 10.1002/1521-3773(20001002)39:19<3348::AID-ANIE3348>3.0.CO
  • [10] 2-X